The book presents the latest advances, innovations, and applications in the field of innovative medicine facilities, as presented by architects and engineers at the International Scientific and Practical Conference Engineering, Construction and Infrastructure Solutions for Innovative Medicine Facilities, held in St. Petersburg, Russia, on May 19-21, 2021. It covers a wide diversity of topics, including the global challenges of our time and the challenges of developing the infrastructure of innovative medicine; current issues of engineering and construction of medical facilities during the pandemic; current issues of engineering and construction of biomedical research infrastructure; formation and development of a comfortable environment for the protection of public health; biological and environmental safety in the engineering, construction and technical operation of biomedical facilities. The contributions, which were selected by means of a rigorous international peer-review process, highlight numerous exciting ideas that will spur novel research directions and foster multidisciplinary collaborations.