Cardiac Electrophysiology: From Cell to Bedside 4th Edition

by Douglas Zipes (Author), Jose Jalife (Author)

Here’s today’s most authoritative and up-to-date information on basic and clinical electrophysiology. The 4th Edition covers everything from fundamental explanations of currents and channels, through the theoretical and experimental bases of cardiac electrical activity and arrhythmias, to current clinical understandings of arrhythmias and their treatment. It also features the most comprehensive updating and revision to date.

Reviews the entire spectrum of research efforts in cardiac electrophysiology.

Details the mechanisms as well as evaluation and management approaches for the full range of arrhythmias encountered in practice.

Covers today’s hottest topics, including HCN channels

stretch-activated channels

inward rectifier channels

contraction-excitation feedback

verve sprouting and arrhythmias

mechanisms of atrial fibrillation

mechanisms of ventricular fibrillation

transgenic and knockout models of cardiac arrhythmias

pharmacogenomics and cardiac arrhythmias

Brugada syndrome

and more.

Features the expertise of 57 new contributors; and, existing contributors have revised and updated completely different chapters from previous editions.

Presents 23 new chapters, including Stretch Activated Channels in the Heart · Biophysical Properties of Inward Rectifier Channels

Human Molecular Genetics and the Heart

Human Genetics of Channelopathies

and more.

Includes revised and updated discussions of calcium channels

voltage regulated potassium channels

membrane pumps and exchangers

connexins

homomeric and heteromeric gap junctions

pharmacology of L-type and T-type channels in the heart

mechanisms of AV nodal excitability and propagation

theory of reentry

rotors and spiral waves in two dimensions

electrical remodeling and chronic atrial fibrillation

mechanisms of initiation of ventricular tachyarrhythmias

atrial fibrillation

ventricular tachycardia

long QT syndrome

Torsades de pointes

and more!

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