Lifestyle change is universally recommended for patients with type 2 diabetes and cardiometabolic disease, yet, the majority of clinical practice, educational programs, and clinical trials within these chronic disease spaces focus on medication use and procedures, with insufficient emphasis on lifestyle medicine.  The concept of lifestyle medicine can serve as a countermeasure, acting through aspects of personal choice, natural and built environments, cultural traditions, and socioeconomic influences that affect the metabolic health of an individual.  Integrating Lifestyle Medicine for Prediabetes, Type 2 Diabetes, and Cardiometabolic Disease provides clinical evidence for and a mechanistic understanding of the six pillars of lifestyle medicine.  It guides the reader to identify opportunities for early intervention rather than focus on the diagnosis and treatment of the established disease. Interventions at earlier points have the potential to mitigate progression, prevent complications, reduce costs, and improve a patient’s overall health at all points in their lifetime.