2025-2026 Basic and Clinical Science Course, Section 9: Uveitis and Ocular Inflammation

by Wendy M. Smith (Author)

Section 9 of the Academy’s Basic and Clinical Science Course™ (BCSC®) begins with an overview of immune-mediated eye disease, summarizing basic immunologic concepts, ocular immune responses, and special topics in ocular immunology.

BCSC Section 9 covers diagnostic considerations, therapies, and complications for uveitis. This volume reviews noninfectious (autoimmune) and infectious forms of uveitis. A table summarizes selected systemic immunomodulatory medications used to treat noninfectious uveitis. Additionally, a discussion on nonbacterial causes of infectious uveitis includes a subsection on SARS-CoV-2 and COVID-19.

Other topics in Section 9 include scleritis, ocular involvement in HIV infection/AIDS, endophthalmitis, and masquerade syndromes. Posterior uveitis and panuveitis are spread into two chapters to make the content more manageable. In addition, a second appendix about antimicrobial agents for intraocular injection is included.

Photos, Clinical Pearl boxes, and other sidebars appear throughout the book, presenting information that can be quickly applied to clinical practice. Increase your understanding with seven videos (sample) and one interactive activity. Both print and eBook users can access to the videos and activity.

Upon completion of Section 9, readers should be able to:

• Describe the immunologic and infectious mechanisms involved in the development of and complications from uveitis and related conditions, including AIDS
• Identify general and specific pathophysiologic processes in acute and chronic ocular inflammation that affect the structure and function of the uvea, lens, vitreous, retina, and other adjacent tissues
• Distinguish infectious from noninfectious uveitic entities

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