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Voltage-gated Ca2+ Channels: Pharmacology, Modulation
Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (Handbook of Experimental Pharmacology 279)
Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (Handbook of Experimental Pharmacology 279)

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The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.

Key Themes:

  1. Voltage-Gated Ca²⁺ Channels (VGCCs):
    • Focus on the function and regulation of VGCCs, crucial for many physiological processes like muscle contraction and neurotransmitter release.
  2. Ca²⁺ Channelopathies:
    • Exploration of diseases caused by mutations in pore-forming subunits, accessory subunits, and channel-interacting proteins of VGCCs.
  3. Novel Regulatory Pathways:
    • New insights into molecular pathways that regulate VGCCs, enhancing understanding of calcium homeostasis.
  4. Subtype-Selective Pharmacological Modulation:
    • Advances in developing drugs targeting specific VGCC subtypes, aiming for precise treatments with fewer side effects.
  5. Channel Interactions:
    • Role of accessory subunits and channel-interacting proteins in VGCC function, regulation, and modulation.

 

 

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Description

Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (Handbook of Experimental Pharmacology 279)

by  Jörg Striessnig (Editor)

Significance:

  • Comprehensive Resource: In-depth look at VGCC biology, useful for researchers and clinicians in cardiology, neurology, and pharmacology.
  • Therapeutic Potential: Focus on selective drug modulation offers clinical applications for diseases like epilepsy, cardiac arrhythmias, and migraine.
  • Advances in Research: Highlights cutting-edge discoveries in Ca²⁺ channelopathies and their molecular underpinnings.

 

Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (Handbook of Experimental Pharmacology 279) available at Book delivery.com for home delivery and cash on delivery all over Pakistan. You can contact for all kind of Medical Books.

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